In 2021, the Promotion of Proper Human Sexual Rights and Ghanaian Family Values Bill was proposed in Ghana to criminalize LGBTQ+ activities, prohibit advocacy, and mandate ‘rehabilitation’ of children in the community. This paper critically examines how the Bill infringes upon certain fundamental human rights guaranteed under the 1992 Constitution of Ghana and International Human Rights law. The paper makes an imperative call for the Bill’s withdrawal or rejection due to its unconstitutional nature and the potential for state-sponsored discrimination.